Khyati Pathak, Ph.D.

Dr. Pathak received her Ph.D. in Microbiology from Sardar Patel University, India. Her sub-sequent post-doctoral training took place at University of Minnesota with Dr. Turesky and, most recently, at TGen with Dr. Pirrotte.

In 2021, Dr. Pathak was named Head of the Metabolomics unit, which operates under the direct leadership of Dr. Pirrotte. In this role, she is responsible for the development of novel analytical assays as well as the successful execution collaborative research projects in metabolomics or lipidomics. To date, Dr. Pathak has developed and validated more than 15 mass spectrometry-based assays to quantify small molecules and metabolites which are routinely performed in the metabolomics unit. Over the years, she has conducted several large cohort studies on a wide variety of clinical and non-clinical, samples.

As a Research Assistant Professor in the Early Detection and Prevention Division, Dr. Pathak’s research is focused on utilizing untargeted and quantitative metabolomics as well as lipidomics approaches to understand metabolic deregulation in pathological conditions including cancer, neurological disorders, and infectious diseases. She leverages this knowledge in early detection to predict disease progression and to identify therapeutic targets. At present, Dr. Pathak’s research is primarily focused on understanding the mechanism of reversal of deregulated energy metabolism upon targeting polyamine metabolism in medulloblastoma. Her research also explores exposome where she is interested in biomonitoring environmental toxicants and carcinogens to understand their effect on human health.