Miracle Hall

Whole Genome Sequencing is a comprehensive method for analyzing genomes. Genomic data is instrumental in identifying mutations that can be used to identify cancer progression and disease outbreaks. The goal of this project is to reduce the cost of whole genome sequencing by reducing library preparation reaction volumes. In successfully completing this goal, we will be able to confirm that lowering reagent volumes and DNA input can produce the same sequencing conversion efficiency. Conversion efficiency is calculated by comparing how much DNA we use for input and how much DNA we recover after the library is created.